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ABC transporters explored in UK conference

published about 16 hours ago
(Biochemical Society) ABC transporters -- the protein superfamily involved in tumor resistance, cystic fibrosis and numerous inherited diseases -- will be explored in an upcoming UK conference.ATP Binding Cassette Transporters: From Mechanism to Organism takes place April 16-18, 2015, at the University of Chester, UK. Early bird registration closes on March 18, 2015.

Oncologists see gene expression profiling tests as helpful but have concerns

published about 16 hours ago
(St. Michael's Hospital) Oncologists praise gene expression profiling tests as a decision-making tool for women with early-stage breast cancer but also have significant reservations.

Menopausal hormone therapy does not affect the risk of dying, study shows

published about 16 hours ago
(The Endocrine Society) Menopausal hormone therapy does not have a significant effect on death, according to a new review of the medical literature published over the past three decades. The results, which included studies with follow-up as long as 18 years, will be presented Friday at the Endocrine Society's 97th annual meeting in San Diego.

Review article provides new insights on how tumors metastasize

published about 16 hours ago
(Boston University Medical Center) In a review article recently published in the journal Clinical and Translational Medicine, researchers from Boston University School of Medicine shed new light on the underlying processes of tumor metastasis and highlight the role of epigenetics in this process.

Chromosomal rearrangement is the key to progress against aggressive infant leukemia

published about 16 hours ago
(St. Jude Children's Research Hospital) The St. Jude Children's Research Hospital -- Washington University Pediatric Cancer Genome Project reports that a highly aggressive form of leukemia in infants has surprisingly few mutations beyond the chromosomal rearrangement that affects the MLL gene. The findings suggest that targeting the alteration is likely the key to improved survival. The research appeared online ahead of print this week in the scientific journal Nature Genetics.