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Precise and programmable biological circuits

published 1 day ago
(ETH Zurich) A team led by ETH professor Yaakov Benenson has developed several new components for biological circuits. These components are key building blocks for constructing precisely functioning and programmable bio-computers.

Useful markers to predict response to chemotherapy in patients with liver cancer

published 1 day ago
(IDIBELL-Bellvitge Biomedical Research Institute) A study led by the researcher at the Institute of Biomedical Research, Isabel Fabregat, could serve to select patients with hepatocellular carcinoma unresponsive to most frequently used drug in liver cancer: sorafenib. The study, published in the International Journal of Cancer describes how tumor cells that have a less differentiated phenotype (mesenchymal) and expresses CD44, do not respond to sorafenib action.

Experimental breast cancer drug holds promise in combination therapy for Ewing sarcoma

published 1 day ago
(St. Jude Children's Research Hospital) Ewing sarcoma tumors disappeared and did not return in more than 70 percent of mice treated with combination therapy that included drugs from a family of experimental agents developed to fight breast cancer, reported St. Jude Children's Research Hospital scientists.

TCGA study improves understanding of genetic drivers of thyroid cancer

published 1 day ago
(NIH/National Human Genome Research Institute) An analysis of the genomes of nearly 500 papillary thyroid carcinomas -- the most common form of thyroid cancer -- provided new insights into the roles of frequently mutated cancer genes and other alterations driving disease development. The findings also may help improve diagnosis and treatment. Investigators with The Cancer Genome Atlas project identified new molecular subtypes that will help clinicians determine which tumors are more aggressive and which are more likely to respond to ... more

Cancer exosome 'micro factories' aid in cancer progression

published 1 day ago
(University of Texas M. D. Anderson Cancer Center) Exosomes, tiny, virus-sized particles released by cancer cells, can bioengineer micro-RNA molecules resulting in tumor growth. They do so with the help of proteins, such as one named Dicer.