Catheter-directed therapy should be considered a first-line treatment option for massive blood clots in the lungs, according to study of nearly 600 patients in Journal of Vascular and Interventional RadiologyCatheter-directed therapy or catheter-directed thrombolysis—an interventional radiology treatment that uses targeted image-guided drug delivery with specially designed catheters to dissolve dangerous blood clots in the lungs—saves lives and should be considered a first-line treatment option for massive pulmonary embolism, note researchers in the November Journal of Vascular and Interventional Radiology."Modern catheter-directed therapy for acute pulmonary embolism saves lives, and we need to raise awareness about its safety and effectiveness not only among the general public but also within the medical community.